Smaller TIPS for severe liver shrinkage and bleeding
Part of Brain & nervous system, Digestive system, Hormones & metabolism clinical trials.
This trial tests a smaller version of a TIPS procedure (a tube placed in the liver to reduce pressure) for people with cirrhosis, a small liver, and a history of serious bleeding from the esophagus or stomach. The goal is to see if this tailored approach can help control bleeding while keeping the liver working as well as possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cirrhosis (scarring of the liver).
- You have had bleeding from enlarged veins in your esophagus or stomach at some point.
- Your liver function score (Child-Pugh or MELD) is within a certain range, meaning your liver is working moderately well.
- An imaging scan shows your liver is smaller than normal (less than 1000 cubic centimeters).
- You are not currently being treated for cancer or have a condition that would shorten your life.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a TIPS stent graft (a tiny mesh tube placed in the liver to relieve pressure) for people with cirrhosis and complications like bleeding or fluid buildup. It aims to see how well it works and if it's safe.
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
This study tests a new version of a device (VIATORR TIPS) that helps lower high blood pressure in the liver for people with cirrhosis. The device is placed to create a small channel that reroutes blood flow and reduces pressure.
This trial tests if an artificial intelligence (AI) system can help guide a TIPS procedure, which is a treatment to improve blood flow in the liver. If you need this procedure and are in good enough health, you may be able to join.
This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.
This trial tests a slightly smaller TIPS stent (underdilated) against the standard size to see which is better at preventing another variceal bleed in people with cirrhosis and liver scarring. It aims to find the safest way to lower pressure in the veins while reducing side effects.
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