Ultrasound for Alzheimer's: Opening the blood-brain barrier
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether a focused ultrasound treatment can safely open the blood-brain barrier in people with Alzheimer's or mild cognitive impairment. The goal is to see if this helps clear amyloid and tau proteins from the brain, which might slow down memory loss.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 50 years old.
- You have been diagnosed with mild cognitive impairment (MCI) or Alzheimer's disease (AD).
- Your memory and thinking test score (MMSE) is between 12 and 26.
- You do not have major depression or other conditions that could affect the results (as checked by a short questionnaire).
- A PET scan shows you have amyloid plaques and tau tangles in your brain.
- You are able to understand and sign a consent form yourself.
- You are not currently taking blood thinners or certain Alzheimer's medications like aducanumab or lecanemab.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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