Clin2
NCT06601335Possibly a fitRecruiting

New immunotherapy combo for head and neck cancer

Head and Neck Squamous Cell Carcinoma

Part of Cancer clinical trials.

This trial tests a new combination of two immunotherapy drugs (AK112 and AK117) versus the standard immunotherapy pembrolizumab for people with advanced head and neck cancer that hasn't been treated before.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
510 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have head and neck cancer (specifically in the mouth, throat, voice box, or lower throat) that has spread or come back and cannot be cured with local treatments.
  • You have not had any previous cancer treatment for this condition (like chemo or immunotherapy).
  • Your cancer must test positive for a protein called PD-L1 (CPS score of 1 or higher).
  • You are able to do your daily activities with little or no help (ECOG score 0 or 1).
  • You have at least one tumor that can be measured on a scan (not in the brain).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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