Clin2
NCT06620393Possibly a fitNot yet recruiting

Dexmedetomidine for reducing agitation after severe brain injury

Traumatic Brain InjuryAgitation,Psychomotor

Treatments studied

Part of Brain & nervous system, Injuries & trauma clinical trials.

This study tests whether a drug called dexmedetomidine (a sedative) can help calm patients with severe brain injury who are on a breathing machine in the intensive care unit. If you or your loved one is in this situation, this treatment might reduce agitation and improve recovery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
72 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You have a moderate to severe traumatic brain injury, confirmed by a doctor.
  • You are currently on a breathing machine (ventilator).
  • You are expected to stay in the intensive care unit for at least 48 hours.
  • You are not at high risk of dying soon, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06993194Not yet recruiting
Comparing two medicines for calming ICU patients with brain injury

This study tests two medications, haloperidol and dexmedetomidine, to see which works better for reducing confusion and agitation in patients who are on a breathing machine after a traumatic brain injury. If you or a loved one is in the ICU with a brain injury and is restless or confused, this trial may help find better ways to manage those symptoms.

NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal

This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.

Sohag
NCT07807579Not yet recruiting· Phase 4
Comparing two sedatives for moderate brain injury

This trial compares two commonly used sedatives to see which one is safer for pressure inside the brain after a moderate head injury. If you qualify, you'll receive one of the two drugs to help your brain recover.

NCT07542990Not yet recruiting· Phase 3
Sedation drug for children on breathing machines in intensive care

This study tests a drug called dexmedetomidine to help sedate children who need a breathing machine for more than 12 hours. It may reduce confusion (delirium) compared to usual sedatives.

Angers
NCT07678216Not yet recruiting
Comparing sedatives for brain swelling after injury

This trial compares three common sedative medications used to control pressure inside the skull after a traumatic brain injury. The goal is to see which medication works best and is safest for recovery.

Asyut, Asyut Governorate
NCT06251375Not yet recruiting· Phase 4
Early sedation for older patients on breathing machines

This study tests an early sedation medicine called dexmedetomidine in patients 65 and older who need a breathing tube. It may help reduce confusion and time on the machine compared to usual care.

Toronto, Ontario

Hear when a new Traumatic Brain Injury trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.