Comparing two sedatives for ICU patients with brain injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma, Mental health clinical trials.
This trial tests two medicines, haloperidol and dexmedetomidine, to see which one works better for calming confusion and agitation in ICU patients who have a traumatic brain injury and are on a breathing machine. If you qualify, the study may help your doctors choose the best treatment for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a confirmed traumatic brain injury
- You are in the intensive care unit (ICU) and on a breathing machine (ventilator)
- Your sedation level (RASS score) is between -5 and +4
- You have been in the ICU for at least 48 hours
- You do not have serious liver or kidney problems, a long QT heart condition, or a history of certain mental health disorders
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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