Gene therapy trial for wet age-related macular degeneration
Part of Eyes & vision clinical trials.
This trial tests a new CRISPR-based gene therapy injected into the eye to treat wet age-related macular degeneration (AMD). It aims to stop the growth of abnormal blood vessels that damage your vision.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old.
- You have active wet AMD with abnormal blood vessels in one eye (the study eye).
- Your vision in that eye is between roughly 20/40 and 20/400 (some limits depending on the dose group).
- You have not had gene therapy or oligonucleotide therapy before.
- You have not had eye surgery in the study eye within the last 3 months.
- You do not have other eye diseases that could affect your central vision, such as uncontrolled glaucoma or significant scarring in the study eye.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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