Trial of ENN0403 to prevent kidney injury after heart surgery
Part of Heart & circulation, Kidney & urinary clinical trials.
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for heart surgery that uses a heart-lung machine (such as bypass, valve surgery, or aortic surgery).
- You must have certain risk factors that make acute kidney injury more likely (your doctor will check which ones apply to you).
- Your kidney function must not be severely reduced (eGFR must be 20 or higher).
- You cannot have had a recent cardiac emergency like needing a pacemaker, ventilator, or CPR within the last 1–2 weeks.
- You must not be pregnant or planning a pregnancy, and if applicable, use effective birth control for 3 months after the study drug.
- You cannot have taken part in another clinical trial within the past month.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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