Inhaled nitric oxide to prevent kidney injury after heart surgery
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether breathing in a gas called nitric oxide during and after heart surgery can help prevent kidney damage. The treatment is given through a mask or tube to support kidney function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must be scheduled for non-emergency heart surgery on a heart-lung machine (such as valve repair/replacement or coronary artery bypass).
- Your kidney risk score must be 2 or higher, as calculated by the study team.
- You cannot have severe kidney disease (on dialysis, transplant, or very low kidney function).
- You cannot have heart failure requiring special support devices or very weak heart pump (ejection fraction below 30%).
- You cannot be taking certain medications that harm kidneys within 24 hours before surgery, or have hemophilia, active infection, or be pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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