Testing a new approach for septic shock patients
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- You have septic shock (a severe infection causing low blood pressure) and need fluids.
- You have signs of poor blood flow, like cold hands or feet, low urine output, or confusion.
- You do not weigh more than 160 kg (about 353 lbs).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to manage fluids and blood pressure medicines in patients with septic shock. It aims to find if using a specific blood flow measurement (capillary refill time) can improve outcomes compared to standard care.
This trial tests whether using specific safety signals can prevent harm from too much fluid given during septic shock. It may help guide doctors to stop fluids at the right time.
This trial examines how the renin-angiotensin-aldosterone system (a hormone system that helps control blood pressure) changes in patients with septic shock, compared to those with sepsis without shock, cardiogenic shock, and healthy volunteers. The goal is to better understand these changes and possibly improve treatment.
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
This study tests if giving fewer fluids (other than the fluids to keep blood pressure up) can help people recover from septic shock. It compares a reduced fluid strategy to the usual care in the ICU.
This study looks at whether a metabolite (nutrient) supplement can help the body’s cells work better when someone is in septic shock. It is done in the ICU, and it may benefit people with sepsis who still have poor circulation and high lactate levels despite standard treatment.
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