Genistein for heart failure from ATTR amyloid cardiomyopathy
Treatments studied
Part of Brain & nervous system, Genetic & congenital, Hormones & metabolism clinical trials.
This trial tests whether genistein, a plant-based supplement, can help people with a specific type of heart disease called ATTR amyloid cardiomyopathy. You might join if you have heart failure with reduced pumping function and this rare protein condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 80 years old
- You have heart failure with a weak heart pump (ejection fraction less than 40%)
- You have been diagnosed with ATTR amyloid cardiomyopathy (a condition where abnormal proteins build up in the heart)
- Your heart failure medicines have been stable for at least 3 months
- You have a certain level of a heart stress marker (NT-proBNP) in your blood
- You do not have uncontrolled diabetes, liver or kidney problems, or certain cancers or breast conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether a structured exercise training program is safe and helpful for people with transthyretin (ATTR) cardiac amyloidosis. It may help improve fitness and daily functioning, and it may also compare groups for specific eligibility needs.
This trial uses heart scans to see how the drug acoramidis affects heart structure and function in people with a specific type of heart disease called ATTR cardiomyopathy. It may help doctors understand if the treatment is working.
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
This study tests whether a daily supplement called genistein, derived from soy, can help reduce the risk of heart problems in people living with HIV. It aims to see if genistein can improve blood vessel function and lower inflammation, potentially protecting your heart.
This study tests whether genistein, a natural compound found in soy, can help reduce inflammation and improve heart health in people who have had a heart attack and are overweight or have other risk factors.
This study tests a new treatment, NTLA-2001, for people with a type of heart disease called transthyretin amyloidosis with cardiomyopathy. It aims to see if the medicine can help improve heart function and quality of life.
Hear when a new Amyloid Cardiomyopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.