Genistein for heart failure from ATTR amyloid cardiomyopathy
Treatments studied
Part of Brain & nervous system, Genetic & congenital, Hormones & metabolism clinical trials.
This trial tests whether genistein, a plant-based supplement, can help people with a specific type of heart disease called ATTR amyloid cardiomyopathy. You might join if you have heart failure with reduced pumping function and this rare protein condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 80 years old
- You have heart failure with a weak heart pump (ejection fraction less than 40%)
- You have been diagnosed with ATTR amyloid cardiomyopathy (a condition where abnormal proteins build up in the heart)
- Your heart failure medicines have been stable for at least 3 months
- You have a certain level of a heart stress marker (NT-proBNP) in your blood
- You do not have uncontrolled diabetes, liver or kidney problems, or certain cancers or breast conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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