Citrulline for sickle cell pain crisis
Treatments studied
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 4 to 21 years old and have any type of sickle cell disease.
- You must be in the hospital with a sickle cell pain crisis that requires strong pain medicine (opioids) through an IV.
- Your pain should have started within the last 3 days, not longer.
- You must be able to start the study drug within 12 hours of your first dose of opioid pain medicine in the emergency room.
- You cannot have had more than 9 hospital stays for pain in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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