Comparing pain medicines for sickle cell crisis in hospital
Part of Blood & lymphatic, Brain & nervous system, Genetic & congenital clinical trials.
This trial compares different ways to manage sickle cell pain crises in the hospital, using a flexible 'platform' design to test combinations of pain medicines. It aims to find the safest and most effective approach to reduce pain and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have sickle cell disease (types SS, SC, or S-beta-thalassemia).
- You are in the hospital because of a pain crisis (acute pain in arms, legs, ribs, chest, or back).
- You need a strong painkiller like morphine through an IV.
- You are not pregnant or breastfeeding.
- You have not already been on IV morphine for more than 24 hours for this crisis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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