L-citrulline for young people with sickle cell pain crisis
Treatments studied
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial tests an IV medication called L-citrulline for children, teens, and young adults (ages 6–21) with sickle cell disease who are having a sudden, severe pain crisis (called a vaso-occlusive crisis). The goal is to see if it helps relieve pain quickly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sickle cell disease (any type).
- You are between 6 and 21 years old.
- You are having a sickle cell pain crisis with severe pain (score 6 or higher on a 0–10 pain scale).
- You are not currently having any other serious sickle cell complications (like stroke, acute chest syndrome, or severe anemia).
- Your current pain started within the last 3 days.
- You have not been hospitalized for sickle cell pain more than 9 times in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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