TAVI for severe aortic stenosis in cardiogenic shock
Part of Heart & circulation clinical trials.
This study tests whether a procedure called TAVI (a valve replacement done through a tube in the leg) can help people with severe aortic stenosis who are in cardiogenic shock, a dangerous condition where the heart can't pump enough blood. The goal is to see if urgent valve replacement improves survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic stenosis (aortic valve area < 1 cm²) and are in cardiogenic shock (low blood pressure, high lactate, weak heart, or have fainted and need a breathing tube).
- No brain bleed in the past month.
- Life expectancy is at least 6 months from other causes.
- Your body mass index (BMI) is between 15 and 40.
- You are not severely frail (Clinical Frailty Score under 6 before this episode).
- No severe lung disease (FEV1 or DLCO less than 25% of expected).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether TAVI (a procedure to replace your heart valve without open-heart surgery) can be done safely at centers that do not have on-site heart surgery backup. It looks at how well patients do after the procedure, focusing on safety and recovery.
This study looks at how well the new heart valve works after a TAVI procedure, using pressure measurements to see if blood flow improves. It aims to confirm that the treatment is effective for people with severe aortic stenosis.
This study tests whether a less invasive valve replacement (TAVI) can be done safely in hospitals that don't have a full heart surgery team on site. If you have severe aortic stenosis and are 70 or older, this trial might offer a new option with a shorter recovery than open-heart surgery.
This study compares two ways of guiding a procedure to replace your aortic heart valve: using ultrasound (echo) instead of the usual X-ray (fluoroscopy). The aim is to see if the ultrasound method works just as well and is safer.
This registry follows people with severe aortic valve narrowing (and sometimes a worn-out valve) who are considered good candidates for TAVI, a valve-replacement procedure. It helps doctors better understand outcomes and care over time.
This study tests a catheter-based procedure to replace a narrowed aortic valve without traditional open-heart surgery. It's designed for patients who are at higher risk for surgery due to age, health conditions, or anatomy.
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