Targeting brain blood vessels to help small vessel disease
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 to 90 years old
- You have been diagnosed with cerebral small vessel disease (a condition affecting tiny blood vessels in the brain)
- You have mild memory or thinking problems (but not dementia)
- You have a specific genetic type (AA) at a certain location in your DNA
- You are willing to provide a blood sample for genetic testing
- You are not taking certain medications (like some antibiotics, antifungals, or St. John's wort)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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