IV plus oral vs. oral-only amiodarone after AFib ablation
Treatments studied
Part of Heart & circulation clinical trials.
This study compares two ways of giving the heart-rhythm medication amiodarone—through an IV followed by pills, versus pills alone—after a standard catheter ablation procedure for people with persistent atrial fibrillation (long-lasting irregular heartbeat). The goal is to see which method better prevents AFib from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an irregular heart rhythm called persistent atrial fibrillation (episodes lasting a week or more) and are getting your first catheter ablation procedure to fix it.
- You've tried at least one heart-rhythm medication (like flecainide or amiodarone) and it didn't work or caused side effects.
- You are willing to take amiodarone either through an IV or as a pill after the procedure.
- You do not have any medical conditions that make amiodarone unsafe, such as thyroid disease, severe liver or kidney problems, low blood pressure, a very slow heartbeat, or certain heart block problems.
- You are not pregnant or breastfeeding, and you are at least 18 years old.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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