Clin2
NCT06653465Possibly a fitNot yet recruiting

Acetaminophen for preventing confusion after major surgery in older adults

Delirium in Old Age

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests whether giving acetaminophen (Tylenol) through an IV during and after major surgery can help prevent confusion or delirium in older patients. It may help you recover more clearly after your operation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
1,930 people
Ages
65 years and older
Study type
Interventional

Who can take part

  • You are 65 years or older.
  • You are scheduled for a major surgery (not on your heart) that will last more than 2 hours with general anesthesia.
  • You are in generally good health (classified as ASA I-III).
  • You weigh more than 50 kg (about 110 pounds).
  • You do not have a history of Alzheimer's, schizophrenia, Parkinson's, seizures, or other brain or psychiatric conditions.
  • You do not have severe heart problems or unstable circulation, and your kidney and liver function are within safe limits for acetaminophen.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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