Tislelizumab before and after surgery for KRAS-mutated lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests whether adding the immunotherapy drug tislelizumab before and after surgery can help people with a specific type of lung cancer (non-squamous NSCLC with a KRAS mutation) that is stage 2 or 3. It aims to improve treatment outcomes by targeting the cancer early.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have stage 2 or 3 (with N2 node involvement) non-squamous non-small cell lung cancer.
- Your cancer must have a KRAS gene mutation.
- You cannot have received any prior treatment for this lung cancer (like chemotherapy, radiation, or immunotherapy).
- You must be healthy enough for surgery and able to receive platinum-based chemotherapy before and after surgery.
- You must not have active autoimmune disease or lung conditions like interstitial lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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