Clin2
NCT06662877Possibly a fitNot yet recruiting

Drug combination for advanced bile duct cancer after first treatment fails

Biliary Tract CancerSecond Line TreatmentChemotherapyTyrosine Kinase Inhibitor

Part of Cancer, Digestive system clinical trials.

This trial tests a new combination of three drugs (anlotinib, nab-paclitaxel, and S-1) for people with advanced bile duct or gallbladder cancer that has progressed after first-line chemotherapy. The goal is to see if this combination can help control the cancer better than standard second-line options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
206 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You need a confirmed diagnosis of advanced bile duct or gallbladder cancer that has grown or returned after standard first-line chemotherapy (gemcitabine-based).
  • You should be able to do most daily activities on your own (ECOG score 0-1).
  • Your cancer must be measurable on a CT scan (at least 1 cm in size).
  • Your liver, kidney, and blood counts need to be within acceptable ranges (your doctor will check these).
  • You must not have had another cancer (except cured skin or early cervical cancer).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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