Clin2
NCT06665217Likely a fitNot yet recruiting

Testing G-Pola-ZLP for newly diagnosed lymphoma

Diffuse Large B-Cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a combination of three drugs (G-Pola-ZLP) for people with newly diagnosed Diffuse Large B-Cell Lymphoma who have not had chemotherapy before. The goal is to see if this treatment works well and is safe.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
14 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with Diffuse Large B-Cell Lymphoma (a type of blood cancer).
  • You are 18 years old or older.
  • You have not had any chemotherapy treatment before.
  • You are expected to live at least 3 more months.
  • You do not have a serious infection or unstable health condition like heart, liver, or kidney disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06664411Recruiting· Phase 2
Pola-ZR2P for untreated DLBCL

This trial tests a new combination of drugs (Pola-ZR2P) for people with a type of lymphoma called diffuse large B-cell lymphoma (DLBCL) who have not had chemotherapy yet. It aims to see if this treatment is safe and effective.

Beijing, Beijing Municipality
NCT06803693Recruiting· Phase 2
New drug combo for untreated large B-cell lymphoma

This trial tests if adding another drug (X) to a standard chemotherapy mix (Pola-RCHP) works better for people with untreated diffuse large B-cell lymphoma (DLBCL). It is for those whose cancer DNA levels did not drop enough after the first round of treatment.

Shanghai, Shanghai Municipality
NCT07702851Not yet recruiting· Phase 2
Combination therapy for early-relapse DLBCL

This trial tests a combination of two targeted therapies, polatuzumab vedotin and glofitamab, for people with DLBCL that either came back within 12 months of R-CHOP or never went away. The goal is to see if this two-drug approach can help when standard chemotherapy has not worked well.

NCT06522555Recruiting· Phase 3
Testing Pola-ZR2 vs ZR2 for older adults with lymphoma

This trial tests a new combination of drugs (Pola-ZR2) against a standard combination (ZR2) for older adults with newly diagnosed diffuse large B-cell lymphoma. It aims to see if the new mix is more effective and safe.

Shanghai
NCT07502872Not yet recruiting· Phase 2
Combination therapy for first-line treatment of aggressive B-cell lymphoma

This trial tests a combination of three targeted drugs (tafasitamab, polatuzumab vedotin, and glofitamab) as a first treatment for diffuse large B-cell lymphoma or high-grade B-cell lymphoma. It aims to see if this approach can be effective without standard chemotherapy.

Providence, Rhode Island
NCT07012980Not yet recruiting· Phase 2
Targeted drug combo for first-line DLBCL in older adults

This trial tests a combination of three targeted drugs (glofitamab, polatuzumab vedotin, and zanubrutinib) as a first treatment for older adults (70+) with a common type of lymphoma called DLBCL. The goal is to see if this approach is effective and well-tolerated without standard chemotherapy.

Hear when a new Diffuse Large B Cell Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.