Optimizing heart failure medications after valve procedure
Part of Heart & circulation clinical trials.
This trial tests if adjusting heart failure medications after a valve repair can help people with heart failure and a weak heart pump. It aims to find the best treatment plan to improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Had a hospital stay for severe valve disease fixed with a catheter-based procedure
- Have chronic heart failure with reduced pumping strength
- Before leaving the hospital, must have a specific heart stress marker above 900 pg/mL, blood pressure at least 100 mmHg, heart rate at least 60 bpm, and potassium level 5.0 or less
- Were on low doses of standard heart failure medicines at the time of admission
- Live in the Lombardy region of Italy
- Be between 18 and 85 years old and willing to participate
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
This trial is testing a new, less-invasive device to fix the tricuspid valve in the heart for people with severe leakage. It may be an option if you are not a good candidate for traditional open-heart surgery and have tried other treatments.
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
This trial tests a new, less invasive valve device (TricValve) for people with severe tricuspid regurgitation who are not good candidates for open-heart surgery. It aims to see if this device can help your heart pump better and improve your symptoms.
This trial tests a procedure called transcatheter edge-to-edge repair (TEER) for people with a specific type of heart valve leak (functional mitral regurgitation) that is causing heart failure symptoms. The procedure is less invasive than open-heart surgery and aims to improve symptoms and quality of life.
This study tests a procedure to fix a leaky heart valve (mitral valve) in people with heart failure, with the goal of helping them tolerate and benefit from standard heart failure medicines. It asks whether adding this valve repair to optimized medicines is better than medicines alone.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.