Heart failure recovery after valve or coronary surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study tests when to start two heart-protective medications (ARNI and SGLT2 inhibitors) after you've had surgery to fix a valve problem or blocked heart arteries. Researchers want to see if waiting a bit before starting these drugs helps your heart recover better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Heart pumping power (ejection fraction) was 40% or less before surgery
- Had successful surgery or procedure to fix a valve problem or completed coronary artery bypass/stent placement
- Enrolled within 3 months before surgery or 10 days after surgery
- Stable after surgery with specific vital sign requirements (blood pressure, heart rate, no IV medications)
- Able to tolerate two specific heart medications (sacubitril/valsartan and SGLT2 inhibitors) or willing to stop them for 1 week before starting the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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