Venetoclax and azacitidine for AML with minimal residual disease
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether the combination of venetoclax and azacitidine can clear small amounts of leukemia cells that remain after initial chemotherapy (called measurable residual disease or MRD). It is for people with acute myeloid leukemia who have MRD before a stem cell transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have acute myeloid leukemia (AML) with small amounts of disease still detected after at least one round of intensive chemotherapy.
- You are 18 years old or older.
- You are able to perform daily activities with little or no help (ECOG score 0-2).
- Your kidneys and liver are working well enough (kidney function ≥30 mL/min, liver tests within limits).
- You have not had any other treatment for this minimal residual disease.
- You are not pregnant or breastfeeding, and you agree to use effective contraception if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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