Double shock for out-of-hospital cardiac arrest
Part of Heart & circulation clinical trials.
This trial tests a new way of giving two quick shocks to restart the heart in people who have a cardiac arrest outside the hospital. If you had a shockable heart rhythm, this approach might help improve your chances of survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a cardiac arrest outside of the hospital.
- Your heart's rhythm was one that can be shocked (like ventricular fibrillation or pulseless ventricular tachycardia).
- You are 18 years or older.
- You are not pregnant or suspected to be pregnant.
- You are not currently incarcerated.
- You do not have a do-not-resuscitate (DNR) order.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving two shocks in a row (instead of one) helps restart the heart in people who have a cardiac arrest outside the hospital and need a defibrillator.
This trial tests whether giving the heart rhythm medicine amiodarone early after a shockable cardiac arrest improves survival. If you had a cardiac arrest due to a heart rhythm problem that didn't stop after the first shock, this study may be for you.
This trial tests a treatment that uses a blood pressure cuff on your arms to try to protect your brain and organs after your heart stopped outside the hospital. You will be in the intensive care unit, and the study will check if this simple 'remote conditioning' can improve recovery.
This trial tests whether a combination of three medications (epinephrine, vasopressin, and a steroid) given by paramedics before arriving at the hospital can improve survival for adults who have a cardiac arrest outside of a hospital. It is only for patients who are treated by specially trained paramedics and meet specific medical criteria.
This trial tests whether using a machine to pump blood and oxygen (ECPR) right after a witnessed cardiac arrest with a shockable rhythm can improve survival. You might be eligible if you had a witnessed arrest, got bystander CPR, and your first rhythm was shockable, as long as the emergency team can reach the hospital in 30 minutes.
This study looks at an implantable defibrillator (ICD) strategy in people who survived a cardiac arrest caused by an abnormal rhythm (ventricular fibrillation or ventricular tachycardia). It aims to reduce the risk of another dangerous rhythm after the blocked heart arteries are fully treated.
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