Effect of one dose of tiotropium on early asthma response to allergens
Part of Immune system & allergy, Lungs & breathing clinical trials.
This study tests whether a single dose of tiotropium (a medicine that helps open airways) can reduce the immediate reaction to allergens in people with mild asthma. If it works, it might offer a new way to prevent asthma attacks triggered by allergens.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have asthma but are otherwise healthy enough to participate.
- Your lung function is at least 65% of normal for your age and size.
- You are allergic to common allergens like dust mites, grass, cat, or horse, as shown by a skin test.
- You have a mild increase in airway sensitivity, confirmed by a breathing test.
- You have not had a respiratory infection or a significant asthma flare-up in the last 4 weeks.
- You are not pregnant or breastfeeding (if female).
- You are a non-smoker or an ex-smoker with less than 10 pack-year smoking history.
- You have not used your as-needed asthma inhaler (budesonide/formoterol) in the 3 weeks before the allergen challenge.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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