Clin2
NCT06690827Possibly a fitRecruiting

Cd123-targeted car-nk cells for relapsed aml or bpdcn

AML (Acute Myeloid Leukemia)BPDCN (Blastic Plasmacytoid Dendritic Cell Neoplasm)

Part of Blood & lymphatic, Cancer, Skin clinical trials.

This trial tests a new treatment using your own immune cells (natural killer cells) that are modified to find and attack cancer cells with a marker called CD123. It is for people with acute myeloid leukemia (AML) or blastic plasmacytoid dendritic cell neoplasm (BPDCN) that has come back or not responded to standard therapies.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old
  • Your cancer cells have a protein called CD123 (confirmed by a lab test)
  • You have acute myeloid leukemia (AML) or blastic plasmacytoid dendritic cell neoplasm (BPDCN) that has come back or is not responding to treatment
  • You are expected to live at least 12 more weeks
  • You have a performance status score of 0, 1, or 2 (meaning you can do most daily activities on your own)
  • Your heart, kidneys, liver, and blood counts are within acceptable ranges

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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