Dupilumab vs steroid for narrow EoE in young people
Treatments studied
Part of Blood & lymphatic, Digestive system, Immune system & allergy clinical trials.
This study compares two treatments for EoE that has caused narrowing in the esophagus: dupilumab (a biologic injection) versus a topical corticosteroid (a swallowed steroid). It aims to see which works better for teens and young adults to improve swallowing and reduce inflammation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 25 years old and weigh at least 40 kg.
- You have EoE confirmed by a biopsy with a high number of allergy cells (eosinophils) in your esophagus.
- You have trouble swallowing (dysphagia) at least twice a week, on average.
- Your esophagus shows signs of narrowing or scarring (like rings or a stricture) during an endoscopy.
- You haven't had your esophagus stretched during the same endoscopy procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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