Relaxin Agonist to Protect Kidneys During Heart Surgery
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether a drug called R2R01 can help protect your kidneys during major heart surgery. Heart surgery can sometimes damage the kidneys, and this trial is looking to see if this new medication reduces that risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for planned (non-emergency) heart surgery involving a heart-lung machine, such as bypass surgery, valve repair/replacement, or aorta surgery
- You have at least two risk factors for kidney injury during surgery (such as diabetes, high blood pressure, or reduced kidney function)
- Your kidneys are working relatively normally right now, with no current kidney injury
- You weigh between 110 and 265 pounds
- You are not currently on dialysis, have not had a kidney transplant, and do not have advanced kidney disease (stage 4 or worse)
- You are able to understand the study, sign consent, and commit to not becoming pregnant (if applicable) for 90 days after the study drug
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving amino acids during heart surgery can help protect your kidneys. It's for people at high risk of kidney injury after surgery.
This trial tests a new device that helps support kidney function during heart surgery. It is for people with mild to moderate kidney problems who are having bypass or valve surgery.
This trial looks at whether a specific heart-surgery technique (called CLCVP) can help protect kidney function soon after surgery. It is mainly for adults with otherwise normal kidney tests before certain types of heart operations.
This trial tests whether personalized care can prevent acute kidney injury (sudden kidney damage) after heart or major blood vessel surgery. If you are having planned heart valve repair, bypass, or aortic surgery, you may be able to join.
This trial tests whether giving L-arginine (a natural amino acid) soon after heart surgery can help protect your kidneys. It is for adults who had heart surgery with a heart-lung machine and did not have kidney problems before surgery.
This trial tests a treatment made from your own white blood cells to help your kidneys recover after acute kidney injury that happens within 48 hours of heart surgery.
Hear when a new Acute Kidney Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.