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NCT07625553Possibly a fitRecruiting

Relaxin Agonist to Protect Kidneys During Heart Surgery

Acute Kidney Injury

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests whether a drug called R2R01 can help protect your kidneys during major heart surgery. Heart surgery can sometimes damage the kidneys, and this trial is looking to see if this new medication reduces that risk.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
430 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are scheduled for planned (non-emergency) heart surgery involving a heart-lung machine, such as bypass surgery, valve repair/replacement, or aorta surgery
  • You have at least two risk factors for kidney injury during surgery (such as diabetes, high blood pressure, or reduced kidney function)
  • Your kidneys are working relatively normally right now, with no current kidney injury
  • You weigh between 110 and 265 pounds
  • You are not currently on dialysis, have not had a kidney transplant, and do not have advanced kidney disease (stage 4 or worse)
  • You are able to understand the study, sign consent, and commit to not becoming pregnant (if applicable) for 90 days after the study drug

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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