Heat treatment versus surgery for overactive parathyroid glands
Part of Hormones & metabolism clinical trials.
This trial compares two ways to treat primary hyperparathyroidism: a minimally invasive procedure (thermal ablation) that uses heat to destroy the overactive gland, versus surgery to remove it. The goal is to see which approach better manages symptoms and prevents complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have primary hyperparathyroidism, meaning your parathyroid glands make too much hormone, and you either have symptoms like kidney stones, bone pain, or muscle weakness, or you have certain risk factors like high calcium, kidney problems, osteoporosis, or being under 50.
- An imaging test (like an ultrasound) shows that at least one parathyroid gland is enlarged.
- You do not have secondary hyperparathyroidism (high hormone levels caused by kidney disease or vitamin D deficiency).
- You do not have a serious bleeding disorder or severe heart or lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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