Double cord blood transplant for blood cancers
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests using a double (two units) umbilical cord blood transplant as a first-time donor stem cell transplant for adults with certain blood cancers or bone marrow failure diseases. It aims to see if this approach is effective and safe for patients who need a stem cell transplant but lack a fully matched donor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years old or older.
- This is your first stem cell transplant from a donor, but you may have had your own stem cells transplanted before.
- You are scheduled to receive a cord blood transplant.
- You have a blood cancer (like leukemia, lymphoma, or multiple myeloma), a bone marrow disorder (like myelodysplastic syndromes or aplastic anemia), or another malignant blood disease.
- You do not have a serious uncontrolled infection, severe heart or lung problems, or an ECOG performance status of 3 or higher (meaning you are not bedridden more than half the day).
- You agree to participate and follow the study rules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a second transplant using two donated umbilical cord blood units for people whose blood cancer returned after a first stem cell transplant. It aims to offer a potential cure for high-risk blood cancers.
This trial tests a cord blood transplant using strong (myeloablative) chemotherapy to prepare your body, plus post-transplant treatment to reduce graft-versus-host disease (GVHD). It may help certain blood cancers when other transplant options are limited.
This Phase 2 study tests using donated cord blood to treat certain adult blood cancers that are at high risk of coming back. It may help strengthen the body’s ability to rebuild blood and fight the cancer after intensive treatment.
This trial studies transplanting healthy blood-forming cells from an umbilical cord blood donor who is not related to you. It may help people with certain blood cancers, immune disorders, or other serious diseases when a standard transplant plan is needed.
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
This study tests whether using cord blood stem cells (collected from umbilical cords after birth) can help treat high-risk blood cancers in children and young adults when a matched donor is not quickly available. Cord blood transplants may help prevent cancer from coming back.
Hear when a new Adult Double Unit Cord Blood Transplant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.