Study of heart valve disease and events
Treatments studied
Part of Heart & circulation clinical trials.
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have severe or moderately severe aortic stenosis (a narrowed heart valve).
- Your doctor has not said you cannot have the TAVI procedure.
- You are able to understand the study information and give your agreement.
- You do not have another heart condition like amyloidosis (a protein buildup in the heart).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
This study follows adults who are having aortic valve replacement (through surgery or a catheter) to see how often certain outcomes happen after the procedure. You may be asked for blood tests and scans at set times, and some people may also be offered a special CT scan.
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
This study looks at how calcium buildup in the aortic valve affects long-term results after a TAVR procedure (a minimally invasive heart valve replacement). It may help doctors understand which patients do better over time.
This study looks at whether people with both severe aortic valve narrowing and cardiac amyloidosis (a buildup of abnormal proteins in the heart) can benefit from a valve replacement procedure. It may help doctors understand how common this combination is and how to improve care.
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
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