AC591 to prevent nerve damage from oxaliplatin chemo
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a drug called AC591 to see if it can prevent nerve damage (tingling, numbness, pain) caused by oxaliplatin, a common chemo drug for colorectal cancer. It is for people starting CAPEOX chemo after colon cancer surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- You have colorectal cancer that was surgically removed within the last 3 weeks to 2 months, and you will get CAPEOX chemo (which includes oxaliplatin) for the first time
- You are in generally good health, with normal blood counts and liver/kidney function
- You do not have nerve or muscle diseases like Parkinson's or multiple sclerosis
- You do not have severe diabetic nerve damage or active infections like HIV or uncontrolled hepatitis
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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