Ultrasound test for liver stiffness in children with bile flow problems
Part of Digestive system clinical trials.
This study uses a special ultrasound technique called elastography to measure how stiff the liver is in children with cholestatic liver disease. The goal is to see how well this test can detect liver scarring (fibrosis) compared to a liver biopsy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be between 0 and 18 years old.
- Your child must have a confirmed diagnosis of cholestatic liver disease, which is a condition where bile flow is blocked or slow. This can be confirmed by a liver biopsy or by blood tests showing high alkaline phosphatase or high bilirubin.
- The cholestatic liver disease must have been present for at least 3 months.
- Your child cannot have fluid buildup in the belly (ascites) from causes other than the liver disease.
- Your child cannot have any tumors or other growths in the liver.
- Your child cannot have other serious health problems like heart failure, kidney failure, or a mental illness.
- Your child cannot have had a liver transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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