Blood thinner for painful venous malformations
Treatments studied
Part of Blood & lymphatic, Pain clinical trials.
This trial tests an oral blood thinner (a type of drug called a direct oral anticoagulant) to see if it can reduce pain and improve quality of life in people with painful venous malformations. The drug may help by preventing abnormal blood clotting inside the malformation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You weigh more than 50 kg (about 110 pounds).
- You have a venous malformation (a cluster of abnormal veins) that causes pain at level 4 or higher, and this pain affects your daily activities or sleep.
- You are not currently taking blood thinners, antiplatelet drugs, or NSAIDs (like ibuprofen).
- You have not had major bleeding or conditions that increase bleeding risk, such as stomach ulcers, or a recent brain or spinal injury.
- You do not have severe kidney or liver problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding aspirin to standard care can reduce the number of painful blood clots in children with a specific vein condition. It may help lower the frequency of these episodes and improve quality of life.
This trial tests if the blood pressure drug enalapril can reduce pain from venous malformations (abnormal veins). It may help people whose pain limits daily activities or interrupts sleep.
This trial tests whether a medication called apixaban (a blood thinner) can safely prevent blood clots after abdominal or pelvic surgery. It is for people who have a moderate risk of clots and bleeding, and who are not taking other blood thinners.
This trial tests a drug called VMX-C001 to quickly reverse the effects of certain blood thinners (Factor Xa inhibitors) in people who need urgent surgery with a high risk of bleeding. It compares VMX-C001 to standard care to see which is more effective at helping blood clot normally.
This trial compares lower doses of two common blood thinner pills (apixaban and rivaroxaban) to a daily injection (enoxaparin) to prevent blood clots in people receiving treatment for blood cancers like multiple myeloma, lymphoma, or certain other blood cancers.
This study tests if the blood thinner apixaban is safe and effective for cancer patients who have low platelets and a recent blood clot. It may offer a treatment option for those who cannot take standard blood thinners.
Hear when a new Venous Malformation, Low Flow trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.