Abatacept to prevent graft-versus-host disease after omidubicel stem cell transplant
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether adding abatacept to standard care can reduce graft-versus-host disease (a condition where donor cells attack your body) after a stem cell transplant using a special cord blood product called omidubicel. It is for adults with blood cancers who have a suitable cord blood unit available.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a blood cancer and a matching cord blood unit can be made into omidubicel.
- You are 18 years or older.
- Your heart, lungs, liver, and kidneys are working well enough for transplant.
- You can care for yourself and are up and about at least 70% of the time (Karnofsky score 70 or higher).
- If you had a previous stem cell transplant using your own cells, it was more than 6 months ago.
- You agree to use two effective birth control methods or abstain from sex from consent through 100 days after transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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