Two-target CAR T cells for relapsed B-cell blood cancers
Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.
This trial tests a new type of immunotherapy that uses your own immune cells engineered to recognize two cancer targets (CD19 and CD22) to treat B-cell blood cancers that have come back or not responded to standard treatments. It may offer a treatment option when other therapies have stopped working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a B-cell blood cancer (leukemia or lymphoma) that has returned or not responded to at least one prior treatment.
- Your cancer cells must have the CD19 and CD22 markers (confirmed by a lab test).
- You need to have adequate organ function, including enough red blood cells, healthy liver and kidneys, and good heart and lung function.
- You must have an estimated life expectancy of at least 3 months.
- You should be able to perform daily activities with minimal help (ECOG score 0 to 2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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