Atrial fibrillation treatment: Ablation vs. medication
Part of Heart & circulation clinical trials.
This trial compares two ways to treat atrial fibrillation in people with heart failure where the heart's pumping strength is still normal. You'll either get a procedure called ablation to restore normal rhythm or medication to control your heart rate. The goal is to see which approach works better for people like you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have atrial fibrillation, confirmed by a heart monitor or ECG.
- You must have heart failure with symptoms like shortness of breath or fatigue (classified as NYHA class II or III).
- Your heart's pumping strength must be above 40%.
- You must meet specific blood test (NT-proBNP) levels based on recent hospital visits and whether you're in atrial fibrillation at the time of screening.
- You must be on stable heart failure medications for at least one month and on a stable dose of water pills for at least two weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
This study compares two treatments for people with atrial fibrillation (an irregular heartbeat) and a specific type of heart failure. It looks at whether a procedure called catheter ablation (which uses heat to fix the heart's rhythm) works better than taking daily heart rhythm medications.
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
This study compares two different treatment strategies for atrial fibrillation (an irregular heartbeat) in people who also have heart failure. One strategy uses medications only, while the other includes a procedure to restore normal heart rhythm. The goal is to find the best way to improve symptoms and outcomes.
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
Hear when a new Heart Failure With Mildly Reduced Ejection Fraction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.