Pacing, medications, and ablation for atrial fibrillation with heart failure
Part of Heart & circulation clinical trials.
This study compares different treatments—pacing therapy, medications, and catheter ablation—for people who have both atrial fibrillation and heart failure. It aims to find the best way to improve your heart function and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have atrial fibrillation (an irregular heartbeat).
- Your heart's pumping strength (ejection fraction) is 40% or less, measured within the last 6 months.
- You are on a stable regimen of four standard heart failure medications at the highest dose you can handle.
- A recent blood test shows a BNP level of 100 or higher (or NT-proBNP of 400 or higher).
- Your atrial fibrillation has not been continuous for more than 1 year, and you haven't had a prior ablation or certain heart surgeries.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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