Overnight dexamethasone test for aldosterone screening
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial is testing a new way to screen for a hormone problem called primary aldosteronism (which can cause high blood pressure) by giving a steroid pill (dexamethasone) overnight. You may be eligible if you have high blood pressure and an adrenal growth, and are already scheduled for a related hormone test.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 75 years old.
- You have high blood pressure (hypertension) or it's suspected.
- You have a growth on your adrenal gland that looks like a harmless adenoma or hyperplasia.
- Your doctor has already scheduled a test called the 1-mg dexamethasone suppression test (a pill you take to check for mild cortisol problems).
- You are not taking steroids, anti-inflammatory drugs, hormone therapy, birth control pills, or licorice supplements.
- You do not have severe kidney disease, poorly controlled diabetes, severe obesity, active cancer, or other serious health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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