Clinical trials
Primary Aldosteronism clinical trials
Below are recruiting primary aldosteronism clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07688928Recruiting
Finerenone vs spironolactone for high blood pressure from aldosteronism
This trial compares two medicines, finerenone and spironolactone, to see which works better and is safer for lowering blood pressure in people with primary aldosteronism. It may help you if you have high blood pressure caused by too much aldosterone.
DhakaAges 18 years+ - NCT07673445Recruiting
Comparing intensive vs. standard blood pressure control for primary aldosteronism
This trial tests whether a more intensive approach to lowering blood pressure is better than standard treatment for people with primary aldosteronism (a condition where the adrenal glands make too much aldosterone, leading to high blood pressure). It aims to find which strategy reduces the risk of heart problems more effectively.
ChongqingAges Any age - NCT07621458Recruiting
Primary Aldosteronism Blood Test Measurement Study
This study examines how different methods of measuring hormone levels in the blood help identify primary aldosteronism (a condition causing high blood pressure). Researchers want to find the best cutoff values to identify patients who might benefit from surgery to remove part of the adrenal gland.
Seoul, Korea, Republic ofAges 18 years+ - NCT06523465RecruitingPhase 4
Statin plus amlodipine for primary aldosteronism
This trial tests whether combining a statin (usually for cholesterol) with amlodipine (a blood pressure medication) can better treat primary aldosteronism, a hormonal condition that causes high blood pressure. If you have this condition, this study may offer a new way to manage it.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06773663RecruitingPhase 1/Phase 2
New imaging test for adrenal gland hormone disorder
This trial tests a special PET scan that may help doctors find the exact cause of high blood pressure related to an adrenal gland problem. It could help decide if surgery or medicine is the best treatment for you.
BeijingAges 18–80 - NCT07297745Recruiting
Guiding curative treatment for primary aldosteronism with a hybrid steroid
This trial tests whether a special type of steroid medicine can help guide treatment for primary aldosteronism, a condition that causes high blood pressure. If the tests show the problem is in one adrenal gland, you might be able to have surgery to cure it.
Singapore, SingaporeAges 21 years+ - NCT07137364Recruiting
Testing spironolactone with blood pressure drugs for PA
This trial looks at whether adding spironolactone to your current blood pressure medicines works better for people with primary aldosteronism (a condition where your adrenal glands make too much aldosterone, raising blood pressure). You may qualify if you have this form of high blood pressure but have declined surgery or don't have an adenoma.
Chongqing, Chongqing MunicipalityAges 30–65 - NCT07111351Recruiting
Studying hormones and genes in adrenal gland conditions
This study looks at the genes and molecules in people with primary aldosteronism (a condition where the adrenal glands make too much of the hormone aldosterone), primary hypertension (high blood pressure), and healthy volunteers. The goal is to better understand these conditions and find better ways to diagnose and treat them.
Beijing, Beijing MunicipalityAges 18–80 - NCT07027254Recruiting
Can a special PET scan improve surgery for primary aldosteronism?
This study uses a new type of PET scan (called Gallium-68 Pentixafor PET-CT) to help doctors better identify the source of a hormone problem causing high blood pressure. The goal is to see if this scan leads to better surgical outcomes compared to standard methods.
Seoul, Gangnam-guAges 19 years+ - NCT06941116Recruiting
Steroid test to screen for a common cause of high blood pressure
This trial tests whether a simple steroid-based test can help identify a specific type of high blood pressure called primary aldosteronism. If you have high blood pressure that needs medication, this study may help find a treatable cause.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05765786Recruiting
Testing methods to diagnose variable primary aldosteronism
This study looks at better ways to diagnose primary aldosteronism when lab results suggest the condition but standard diagnosis criteria haven’t been met. It may help you understand what your hormone pattern means and whether you need specific treatment.
LondonAges 18 years+ - NCT05368090Recruiting
Ultrasound-guided ablation for primary aldosteronism
This trial studies whether a procedure called endoscopic ultrasound–guided radiofrequency ablation can treat primary aldosteronism (a hormone condition that can raise blood pressure and potassium issues). It may help shrink an overactive adrenal growth and reduce the need for surgery for some people.
BergenAges 18–80 - NCT03224312Recruiting
Study of primary aldosteronism in people with high blood pressure
This trial studies people with high blood pressure caused by a hormone problem called primary aldosteronism. If you qualify, the study may help doctors learn better ways to identify and manage this specific cause of blood pressure elevation.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07298954Recruiting
Comparing adrenal vein sampling methods for primary aldosteronism
This trial compares different ways of doing adrenal vein sampling (a test to find which adrenal gland is causing high blood pressure). It aims to see if combining methods works better than using just one for people with primary aldosteronism.
ChongqingAges 18–70 - NCT06740838Recruiting
Overnight dexamethasone test for aldosterone screening
This trial is testing a new way to screen for a hormone problem called primary aldosteronism (which can cause high blood pressure) by giving a steroid pill (dexamethasone) overnight. You may be eligible if you have high blood pressure and an adrenal growth, and are already scheduled for a related hormone test.
Gdansk, Pomeranian VoivodeshipAges 40–75 - NCT06495983Recruiting
Hormone tracking and data collection in primary aldosteronism
This study tracks hormone levels and collects different health information to better understand primary aldosteronism, a condition where your adrenal glands produce too much aldosterone. It aims to improve diagnosis and care.
BergenAges 18–70 - NCT07691801Recruiting
Testing a New Method to Diagnose a Common Cause of High Blood Pressure
This study uses a new, precise blood test to help diagnose primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. It compares results from healthy volunteers and patients with suspected primary aldosteronism to see if it works better than current methods.
Beijing, Beijing MunicipalityAges 18–70 - NCT07470580Recruiting
Heat treatment vs surgery for adrenal gland tumor
This study compares two treatments for a certain type of adrenal gland tumor (Conn's adenoma) that causes high blood pressure. One is a heat-based procedure called radiofrequency ablation and the other is surgery to remove the tumor. The goal is to see which is better at controlling blood pressure.
ToulouseAges 18 years+ - NCT06108427Recruiting
Renin-guided treatment with aldosterone blockers in primary aldosteronism
This study tests whether adjusting a type of blood pressure medication (called a mineralocorticoid receptor antagonist) based on renin levels is safe and helpful for people with primary aldosteronism. It aims to find a better way to manage the condition.
Montreal, QuebecAges 18 years+ - NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85 - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT07378176Recruiting
Study on outlook for primary aldosteronism patients
This study follows people with primary aldosteronism over time to understand their health outcomes. It may help doctors learn how to better treat this condition.
Chengdu, SichuanAges 18–80 - NCT06635993Recruiting
Testing a PET scan for aldosterone and cortisol condition
This trial tests whether a special PET/CT scan (68Ga-Pentixafor) can accurately identify the subtype of primary aldosteronism in people who also have excess cortisol. It may help determine if surgery is the right treatment for you.
Chongqing, Chongqing MunicipalityAges Any age - NCT06569589Recruiting
Sodium MRI for primary aldosteronism
This study uses a special MRI to measure sodium levels in your body to better understand and treat primary aldosteronism, a condition that can cause hard-to-control high blood pressure. Participating may help doctors learn how to manage your condition more effectively.
SingaporeAges 21–70
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Common questions
- Are there clinical trials for primary aldosteronism?
- Yes. Clin2 currently lists 44 recruiting primary aldosteronism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary aldosteronism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary aldosteronism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.