Balloon vs stent for heart artery blockages in high bleeding risk patients
Part of Heart & circulation clinical trials.
This trial compares a drug-coated balloon (medicated balloon) to a drug-eluting stent (medicated mesh tube) for treating new blockages in heart arteries. It is designed for patients with a high risk of bleeding who have completed a short course of anti-clotting medication and have been event-free for at least one year.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older
- You have stable, chronic chest pain or related symptoms and a new blockage in a heart artery that is at least 2.25 mm wide and can be treated with a drug-coated balloon
- You have a high risk of bleeding (for example, age 75+, low red blood cell count, history of brain bleed, recent bleeding, planned long-term NSAID or steroid use, planned surgery needing to pause anti-clotting drugs, kidney failure, certain blood disorders, severe liver disease, or expected trouble sticking with medications)
- You have already completed a standard, short course of two anti-clotting drugs (1-3 months) and are now taking only one anti-clotting drug for at least one year after the procedure
- You have had no serious bleeding or heart-related events (like heart attack, stroke, or repeat procedures) for at least one year following the initial procedure
- You do not have any of the following: recent or unstable heart attack, known allergy to aspirin or related drugs, need for blood thinners, previous stroke or heart attack, peripheral artery disease, certain high-risk artery blockages (like left main artery, in-stent re-blockage, bypass graft, or complex bifurcation), severe heart failure, severe valve disease requiring surgery, or pregnancy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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