Testing a new inhaler medicine for cystic fibrosis
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study tests an experimental inhalable medicine called ARCT-032 for people with cystic fibrosis who cannot take or benefit enough from current CFTR modulators. The goal is to see if it safely improves lung function and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of cystic fibrosis.
- You are not currently taking CFTR modulators (like Trikafta) or have stopped taking them for at least 2 months because they didn't work, caused side effects, or you can't get them.
- Your lung function (measured by FEV1) is between 40% and 100% of what's expected for someone your age, sex, and height (or 45%–90% for one group).
- You have not had recent moderate to severe coughing up of blood, major surgery, or a transplant.
- You don't need extra oxygen while awake, or more than 2 liters per minute while sleeping.
- You are not on high-dose steroids (like more than 15 mg of prednisone daily) and your liver and kidney function is good.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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