Targeted drug combo for HER2-positive advanced lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination of three drugs (Disitamab Vedotin, Tislelizumab, and Bevacizumab) for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene or protein. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced non-small cell lung cancer that has spread or come back, and it cannot be removed by surgery or cured with radiation and chemo.
- Your tumor has a HER2 mutation, extra copies of the HER2 gene, or high levels of HER2 protein.
- You are age 18 or older.
- You have not had treatment with HER2 antibodies or antibody-drug conjugates before.
- You have not had brain metastases that are not stable or controlled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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