Predicting response to clopidogrel after mild stroke or mini-stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at whether certain blood tests can predict if the antiplatelet drug clopidogrel (Plavix) will work well in people who have had a mild stroke or a mini-stroke (TIA). The goal is to help doctors choose the best treatment for each person.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You had a mild stroke (NIHSS score 3 or less) or a mini-stroke (TIA) with high risk of another stroke (ABCD2 score 4 or more).
- You started taking clopidogrel (Plavix) within 72 hours of your symptoms starting.
- You did not have a severe stroke, did not need clot-busting treatment or mechanical clot removal.
- You do not have heart-related causes of stroke (like atrial fibrillation) or unknown-source embolic stroke.
- You are not taking blood thinners (like warfarin or rivaroxaban), do not have severe liver/kidney disease, are not allergic to clopidogrel or aspirin, and have no bleeding problems or active ulcers.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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