Testing new PET/MR scans for primary aldosteronism
Part of Hormones & metabolism clinical trials.
This study tests two new types of PET/MR scans (68Ga-Pentixafor and 68Ga-FAPI-04) to see if they can better detect the cause of primary aldosteronism — a condition that leads to hard-to-control high blood pressure. The scans may help doctors decide which treatment is best for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have high blood pressure that is hard to control, low potassium, or your doctor suspects or has confirmed primary aldosteronism (a condition where your adrenal glands make too much of the hormone aldosterone).
- You have nodules on one or both adrenal glands seen on a scan.
- You have had a heart ultrasound (echocardiogram) to check for thickened heart muscle.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new imaging method called [18F]CETO PET scan to better understand the cause of high blood pressure due to primary aldosteronism (PA). It may help guide treatment decisions without needing more invasive tests.
This trial tests a special PET scan (using a tracer called PentixaFor) to see if it can help find which adrenal gland is making too much aldosterone in people with primary aldosteronism. The goal is to reduce the need for more invasive tests like adrenal vein sampling.
This trial tests a special PET scan that may help doctors find the exact cause of high blood pressure related to an adrenal gland problem. It could help decide if surgery or medicine is the best treatment for you.
This study compares a newer, less invasive PET/CT scan (using 68Ga-Pentixafor) to the standard adrenal vein sampling test to identify which adrenal gland is causing high blood pressure in people with primary aldosteronism. If you're considering surgery to remove a nodule on your adrenal gland, this trial may help determine the best approach.
This study uses a new, precise blood test to help diagnose primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. It compares results from healthy volunteers and patients with suspected primary aldosteronism to see if it works better than current methods.
This study uses a new type of PET scan (called Gallium-68 Pentixafor PET-CT) to help doctors better identify the source of a hormone problem causing high blood pressure. The goal is to see if this scan leads to better surgical outcomes compared to standard methods.
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