Steroid treatment to prevent heart rhythm problems after TAVR
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether giving a steroid called methylprednisolone before a heart valve procedure (TAVR) can reduce the chance of developing a heart-rhythm problem called left bundle branch block (LBBB). LBBB can cause the heart to beat less efficiently. The study aims to see if the drug helps keep the heart's electrical system working well after the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older.
- You have been chosen to have a TAVR procedure through a catheter (a thin tube inserted into a blood vessel in the leg).
- You do not have a pacemaker already.
- You do not have any severe infections or other life-limiting illnesses (like advanced cancer or organ failure).
- You are not allergic to methylprednisolone (a type of steroid).
- You have not been taking steroid medicines (by mouth, breathing in, or through a vein) for a long time recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people who develop a new heart block (left bundle branch block) after having a minimally invasive aortic valve replacement. Researchers want to find the best way to manage this condition to prevent future heart problems.
This trial tests whether adding a steroid called methylprednisolone during a procedure to place a stent for an unruptured brain aneurysm can reduce side effects and improve recovery. It's a phase 4 study, meaning the drug is already approved for other uses, and researchers are checking if it works well for this specific situation.
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
This trial tests whether giving a medication right after a heart valve replacement can prevent a common type of irregular heartbeat (atrial fibrillation). It compares two medicines to see which is more effective.
This trial tests whether giving a steroid medicine before and after surgery to fix an aortic tear or bulge can reduce the body's overactive inflammatory response (called postimplantation syndrome) after the procedure. If you are having a planned repair for this condition, this treatment might help you recover with fewer side effects.
This trial studies people who had a heart valve procedure called TAVI and later had a heart rhythm problem. You will get a tiny heart monitor placed under your skin to track your heart rhythm over time and help doctors understand how common these problems are.
Hear when a new Left Bundle-Branch Block trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.