Early steroids to prevent heart block after TAVR
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether giving a steroid medication shortly after a TAVR procedure can reduce the chance of developing a heart-rhythm problem called left bundle branch block. This could help your heart beat normally and avoid needing a pacemaker later.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older
- You are scheduled to get a TAVR procedure through the leg artery (transfemoral)
- You do not already have a pacemaker or certain serious heart-rhythm problems
- You are not allergic to the steroid methylprednisolone
- You do not have an active infection in the blood (septicemia)
- You are not currently taking steroid medications by mouth, inhaled, or by IV
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people who develop a new heart block (left bundle branch block) after having a minimally invasive aortic valve replacement. Researchers want to find the best way to manage this condition to prevent future heart problems.
This study tests whether a steroid called methylprednisolone, given soon after a flow diverter stent is placed, can help reduce inflammation and improve outcomes for people with an unruptured brain aneurysm. It is for patients who are already scheduled for this stent procedure.
This trial tests whether giving steroids before a planned aortic repair can prevent a complication called postimplantation syndrome, which causes fever and inflammation. It might help people having elective surgery for a type B aortic dissection or thoracoabdominal aortic aneurysm.
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
This study tests whether stopping beta blockers after TAVI is safe and effective compared with continuing them. It may help clarify the best medication plan after valve replacement for people at higher surgical risk.
This trial is testing whether a single dose of the steroid methylprednisolone, given before heart surgery, can protect your kidneys from damage during the operation. If you qualify, you'll receive the drug or a placebo, and your kidney function will be monitored closely.
Hear when a new Left Bundle-Branch Block trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.