Steroid treatment to prevent postimplantation syndrome after aortic repair
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether giving a steroid medicine before and after surgery to fix an aortic tear or bulge can reduce the body's overactive inflammatory response (called postimplantation syndrome) after the procedure. If you are having a planned repair for this condition, this treatment might help you recover with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type B aortic dissection (a tear in the wall of the main artery) or a thoracoabdominal aortic aneurysm (a bulging area in the chest and belly part of the aorta).
- Your surgery to fix this is planned ahead of time, not done as an emergency.
- You have healthy kidneys and liver (no severe kidney or liver disease).
- You do not have an active infection, autoimmune disease, or uncontrolled diabetes.
- You have not had any previous procedure on your aorta, and you are not allergic to the study drug (methylprednisolone).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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