Lower-dose radiation before stem cell transplant for older adults with aplastic anemia
Part of Blood & lymphatic clinical trials.
This trial tests a lower-dose radiation (TBI) conditioning regimen for stem cell transplants in patients aged 50 and older with aplastic anemia. The goal is to make the transplant safer and more effective for older adults who may not tolerate standard high-dose treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 50 years old or older.
- You must have aplastic anemia, including severe or chronic forms.
- You must not have had a previous stem cell or bone marrow transplant.
- You must not have an active infection that is not controlled or serious organ problems (liver or kidneys).
- You must not have active cancer (except minor skin cancers) or uncontrolled viral infections like HIV or hepatitis.
- You must be able to understand and sign the consent form yourself or have a family member do it.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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