Exosomes for Sjogren's and Dry Eye
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 75 years old.
- You have dry eye (Schirmer's test less than 10 mm in 5 minutes) or Sjogren's syndrome (diagnosed by standard criteria) or you are a healthy person without chronic disease.
- If you are in the Sjogren's group, your immune, liver, kidney, and blood tests must be normal.
- You are not pregnant or breastfeeding.
- You do not have eye inflammation or infection, history of alcohol abuse, diabetes, or a major life-threatening condition.
- You have not had steroid pulse therapy in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at tiny particles and genetic material in tears and blood to better understand dry eye syndrome and Sjögren's syndrome. By comparing these markers between people with these conditions and healthy volunteers, it aims to find better ways to diagnose and treat them.
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
This study looks at people with Sjogren's syndrome, dry eye, or other inflammatory conditions to better understand these diseases. It may help improve diagnosis and treatment.
This study tests a new eye drop treatment made from your own blood serum for severe dry eye that hasn't improved with standard treatments. Researchers will analyze proteins in your tears to understand why this treatment works and who benefits most.
This study follows people who may have Sjögren’s disease to better understand how to diagnose it. If you have symptoms like dry eyes or dry mouth, this could help researchers confirm the diagnosis and learn what tests best explain it.
This early-phase trial tests whether a new treatment using exosomes (tiny natural particles) given as eye drops or injections can help people with Sjögren's syndrome who have severe dry eyes that haven't responded to usual treatments. The goal is to see if it's safe and to get early hints of whether it relieves eye symptoms.
Hear when a new Sjogren's Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.