Clin2
NCT07192666Possibly a fitNot yet recruiting

Exosome therapy for dry eye from Sjögren's syndrome

Sjögren's Syndrome

Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.

This trial tests an exosome treatment for people with Sjögren's syndrome whose dry eye symptoms haven't improved with standard care like artificial tears or steroid drops. The goal is to see if this new approach can help relieve eye discomfort.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
12 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 65 years old.
  • You have Sjögren's syndrome with eye symptoms (like severe dry eye).
  • Your eye problems haven't gotten better after at least 3 months of usual treatments such as artificial tears or steroid drops.
  • You are willing to use effective birth control (if applicable) from the start of the study until 6 months after the last dose.
  • You do not have active eye infections, other serious eye diseases, or eye surgery in the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07185139Not yet recruiting· Early Phase 1
Stem cell contact lenses for dry eye in Sjögren's

This trial tests a special contact lens made from stem cells to treat dry eye caused by Sjögren's syndrome. It may help if standard treatments like artificial tears or steroid drops haven't worked.

NCT07118241Recruiting· Phase 2
Testing a new eye drop for Sjögren's dry eye

This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.

Sydney, New South Wales
NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye

This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.

Taipei, Taiwan
NCT06475027Not yet recruiting
Study of tear and blood particles in dry eye and Sjögren's

This study looks at tiny particles called exosomes and genetic material (miRNA) in tears and blood to better understand dry eye and Sjögren's syndrome. It may help find new ways to diagnose or treat these conditions.

Taipei
NCT07671222Not yet recruiting· Phase 2
Infliximab Eye Drops for Sjögren's Dry Eye

This trial tests whether an eye drop version of infliximab, a medication that reduces inflammation, can help people with Sjögren's syndrome who have severe dry eye. You would keep taking your current medications and add these drops to see if they improve symptoms and eye surface damage.

Mexico City, Mexico City
NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's

This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.

Tianjin, Tianjin Municipality

Hear when a new Sjögren's Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.